Who's not playing this?
I've heard it said that this is the first Grand Theft Auto with a heart. It really is. The protagonist, Niko Bellic, is the first main character in a GTA that you can actually root for. Yes, he's a bad guy- but he's got his reasons. There's also a story here that's second to none in the series as well as a living breathing world that it's all wrapped up in that's going to be very hard for any other game to top.
The 'Godfather' of gaming? Yeah, I think so.